AI isn’t just changing the game—it’s creating entirely new ones. And OpenAI’s latest release, “A Practical Guide to Building Agents,” is your playbook for one of the most powerful moves yet.

The Future Is Agent-Based (And It’s Already Here)
OpenAI just dropped what might be the most important developer resource of 2025: a comprehensive guide to building AI agents that can actually do things on your behalf. Not just answer questions—but execute entire workflows with a level of independence that makes previous automation look like child’s play.
If you thought prompt engineering was where the real money is, hold onto your keyboards—agent engineering is about to become the hottest skill in tech.
What Are AI Agents (And Why Should You Care?)
Let me break this down in a way that’ll make you sound smart at your next meetup:
AI agents aren’t just fancy chatbots. They’re systems that:
- Independently perform tasks with minimal human supervision
- Leverage LLMs to manage workflow execution and make decisions
- Use various tools to interact with external systems
- Work within guardrails to ensure safe, predictable operation
Think of traditional automation as following a strict recipe. AI agents are more like experienced chefs—they understand the goal, adapt to circumstances, and can handle unexpected situations without crashing.
When To Build Agents (And When Not To)
Here’s the key insight many are missing: Agents aren’t for everything.
You’ll want to consider the agent approach when dealing with:
- Complex decision-making that requires nuanced judgment
- Systems with unwieldy, hard-to-maintain rules
- Workflows heavy on unstructured data and natural language
As the guide explains, traditional rules-based automation still wins for simple, deterministic processes. But for tasks that previously resisted automation because they needed a “human touch”—that’s where agents shine.
The Agent Architecture You Need to Understand
The guide outlines two primary approaches to agent design:
- Single-agent systems: One model with appropriate tools executes workflows in a loop—simpler to build and maintain
- Multi-agent systems: Tasks distributed across specialized agents—more complex but better for handling complicated workflows
Within multi-agent systems, two patterns emerge:
- Manager pattern: A central agent coordinates specialized agents via tool calls
- Decentralized pattern: Multiple peer agents hand off tasks to one another
Understanding these patterns is crucial because choosing the wrong architecture can lead to maintenance nightmares down the road.
The Talking Points You Need
Next time someone asks about AI agents, drop these insights:
- “The real breakthrough isn’t better LLMs, but how they’re being orchestrated to perform complex workflows autonomously”
- “The key difference between agents and traditional automation is adaptability—agents can handle edge cases and ambiguity”
- “Guardrails are essential—a layered defense approach combining LLM-based classifiers, rules-based protections, and human oversight”
- “The best implementations start simple and evolve, rather than trying to build fully autonomous systems from day one”
Getting Started: Your Agent Roadmap
If you’re eager to join the agent revolution, follow this progression:
- Start with a single agent that handles a narrow, well-defined workflow
- Add tools incrementally rather than trying to build a do-everything system
- Set up proper guardrails to manage data privacy and reputational risks
- Plan for human intervention when agents exceed failure thresholds or face high-risk decisions
- Evolve to multi-agent architectures only when complexity demands it
The Bottom Line
AI agents represent the next evolution in automation—moving from code that follows rigid rules to systems that understand goals and figure out execution details independently.
As the guide concludes: “Agents mark a new era in workflow automation, where systems can reason through ambiguity, take action across tools, and handle multi-step tasks with a high degree of autonomy.”
For those of us in the AI space, this is the shift we’ve been waiting for—from AI that simply provides information to AI that takes meaningful action in the world.
What’s Your Take?
Have you started experimenting with AI agents yet? Hit reply and let me know what you’re building or what’s holding you back. The best responses might feature in our next issue!
Remember: AI won’t replace you, but someone using AI agents might replace your boss. Let’s make sure that person is you.
Until next time,
Seb
P.S. Want to dive deeper into agent building? Check out the full OpenAI guide here.